John married Maw, Charlotte "Lottie" Isabelle "Lottie" on 21 Sep 1899 in Esquesing, Halton, Ontario, Canada. Charlotte (daughter of Maw, William and McKee, Elizabeth) was born on 11 Oct 1878 in Albion, Peel, Ontario, Canada; and died. [Group Sheet] [Family Chart]

1. Brain, Alfred Edwin was born on 8 Jul 1901 in Hornby, Esquesing, Halton, Ontario, Canada; died on 6 Sep 1981 in , , Ohio, USA; was buried in Sep 1981 in West Park Cemetery, Cleveland, Cuyahoga, Ohio, USA.
2. Brain, Ethel Beatrice was born on 26 Mar 1904 in Hornby, Esquesing, Halton, Ontario, Canada; and died.
3. Brain, Clarkson Alexander was born on 25 Oct 1906 in Toronto, York, Ontario, Canada; and died.
4. Brain, Gladys was born about 1909 in Toronto, , Ontario, Canada; and died.
5. Brain, Gordon was born about 1910 in Toronto, , Ontario, Canada; and died.
6. Brain, Maurice was born on 24 Dec 1912 in Toronto, , Ontario, Canada; and died.

Edwin married Chisholm, Mary Elizabeth on 27 Jan 1870 in Halton, Halton, Ontario, Canada. Mary was born on 26 Oct 1845 in Esquesing, Halton, Ontario, Canada; died on 8 Jul 1906 in , Halton, Ontario, Canada. [Group Sheet] [Family Chart]